Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream activation by the kinase LKB1 is well recognized, the ...

Activating the PPARβ/δ-AMPK metabolic pathway could be an effective strategy to tackle the most common chronic liver disease in the world’s population. A study led by Manuel Vázquez Carrera, group ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

This story is sponsored by Health Utah. For years, the mantra for weight loss has been simple: eat less, move more. But what if everything you've been told about shedding pounds is wrong? Dr. Whit ...