We've got an awesome full album stream to decimate your puny ear drums. Some of death metal's greatest modern musicians have assembled to form extreme metal band Alkaloid, and we've got the exclusive ...

Scorpion venom packs more than a painful sting. It’s also chock full of novel bioactive compounds—most of them polypeptides—that intrigue scientists. For the first time, researchers have identified an ...

Engineered biosynthesis of modified natural products normally uses microbes as biochemical factories. Now, chemical biologists are taking advantage of the largely untapped biochemical potential of ...

All plants mediate their environmental interactions via chemical signals. An example is the alkaloid gramine produced by barley, one of the world's most widely-grown cereals. Gramine provides ...

Plants are undeniably one of nature's most promising sources of new medicines, with monoterpenoid indole alkaloids (MIAs) being a great example. Some intricate compounds are built from multiple-linked ...

What does cannabis, coca leaf, and all coffee have in common? They all contain alkaloids, a powerful group of medicinal compounds found in plants around the world. While little is presently known ...

A step forward in our understanding of how plants produce alkaloids could herald new pharmaceuticals. Biologists from the University of York (UK) have discovered enzymes that catalyze the biosynthesis ...

Researchers have highlighted cases of tropane alkaloid contamination in Italy and called for increased monitoring and regulation. The study detailed recent cases of tropane alkaloid intoxication after ...

Selinexor dose optimization: A retrospective analysis. This is an ASCO Meeting Abstract from the 2024 ASCO Quality Care Symposium. This abstract does not include a full text component.

Indole-based alkaloid natural products such as fischerindoles and hapalindoles have promising antimicrobial and antitumor activities, but they are difficult to make synthetically. New findings on how ...

Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to ...