Encaleret is an oral, small molecule designed to selectively modulate the calcium-sensing receptor protein to restore PTH secretion and calcium reabsorption.

The CALIBRATE study of encaleret for patients with ADH1 met all pre-specified primary and key secondary efficacy endpoints - The primary ...

Calcium plays a pivotal role in numerous physiological processes, ranging from muscle contraction and neuronal signalling to bone formation and blood coagulation. In clinical settings, understanding ...

Urolithiasis, also known as renal lithiasis, is a commonly occurring disease in humans. Calculi are formed in the urinary tract, including the tubular region of the kidney. Calcium phosphate crystals, ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

General laboratory evaluation. Typical post-transplant monitoring labs are shown in Table 2. KDIGO suggests (with low evidence of support) that labs be obtained two to three times per week for weeks 2 ...

Dr. Chidiebere D. Akusobi (Medicine): A 44-year-old woman was evaluated in the rheumatology clinic of this hospital because of proximal muscle weakness and myalgia. The patient had been in her usual ...