Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies. However, nearly half of patients show limited ...

A newly discovered cancer trick that weakens immunotherapy may be stopped by everyday statins.

Subcutaneous immunotherapy injections for cancer, such as immune checkpoint inhibitors, are an emerging therapy that may replace some traditional intravenous infusions. Common side effects include ...

At a time when immunotherapy is playing an increasingly crucial role in the treatment of many cancer types, 20 accumulating results suggest that it will likely be essential to optimize ToDA of immune ...

Prostate cancer is the most common cancer in men throughout the United States. Most men do not realize they have cancer due ...

Cancer immunotherapy has historically focused on harnessing the ability of T cells to recognize and attack cancer cells. Adaptive immune checkpoint inhibitors (ICIs) unleash tumor-infiltrating ...

The role of lipid-laden Kupffer cells in immunosuppression and immunotherapy response in MASLD-related hepatocellular carcinoma. Phase I study of hV01, a recombinant human IL-21-expressing oncolytic ...

CPI treatments such as HCB101 are considered particularly promising forms of immunotherapy because they activate the body's own defenses to kill cancer cells. They work by blocking proteins like CD47 ...

High-grade astrocytoma, which includes glioblastoma, is a fast-growing, aggressive brain cancer that often returns after the tumor is removed, making it difficult to treat. Patients with recurrent ...

A clinical trial shows that combining laser heat therapy with immunotherapy significantly extends the lives of patients with aggressive, recurrent brain cancer.

Existing autoimmune drugs may prevent or reverse a serious side effect faced by patients with cancer. Immunotherapy-induced type 1 diabetes is a serious side effect faced by some patients receiving ...