Applegate's MeSsy podcast co-host Jamie-Lynn Sigler also shares how her two sons have had two very different responses to her own multiple sclerosis struggles. Christina Applegate has been candid for ...

"It’s my last awards show as an actor probably, so it’s kind of a big deal." Christina Applegate is opening up on what work she'll pursue in the future amid her battle with multiple sclerosis. In an ...

Christina Applegate is continuing to speak candidly about her battle with multiple sclerosis. The "Dead to Me" star, 53, became emotional discussing her health in an episode of "Conan O'Brien Needs A ...

Christina Applegate and Jamie-Lynn Sigler read some emails from listeners on the latest episode of their podcast MeSsy With Christina Applegate and Jamie-Lynn Sigler, and seized upon one in part ...

Christina Applegate recorded the latest episode of her “MeSsy” podcast from a Los Angeles hospital bed where she revealed she’s been hospitalized with “so ...