Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

The simplest explanation of cancer is that, for any reason, a cell in our body ignores its biological program and gets loose, multiplying itself again and again, creating a tumor. This has a lot to do ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS) has revealed that mitochondrial stress coordinates chromatin ...

Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...

A new review proposes that misregulation of developmental senescence, a transient embryonic cell-arrest program, may contribute to the congenital defects of CHARGE syndrome through its links to the ...

Taking unconventional paths with no fear of exploring the unknown has been a hallmark of Cigall Kadoch’s work. As a graduate student, the now biochemist and molecular biologist joined a developmental ...

Deep inside the cells that line and support our arteries, a small chromatin-binding protein is quietly shaping the fate of ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...