New research helps explain why disease-associated genetic variants can lead to variable clinical outcomes, influenced both by the patterns of secondary variants, or genetic background, and by how ...

The genetic roots of a disease or disorder do not always grow into clear-cut, easily diagnosed clinical features. Even if a parent and child have the same genetic marker implicated in an outcome, such ...

Asymptomatic hyperuricemia Acute/intermittent gout Advanced gout (or what used to be called chronic tophaceous gout). The rate of progression from asymptomatic hyperuricemia to advanced gout varies ...

Alzheimer’s disease (AD) is clinically characterized by a progressive sequence of symptoms and signs that usually begins with subtle memory and cognitive changes and culminates in profound functional ...

This month, I’d like to discuss the options that are available when an individual has clinical features of any of the three types of NF but genetic testing is negative. Next-generation sequencing (NGS ...

NEW YORK--(BUSINESS WIRE)--Castor, a leading provider of decentralized and hybrid clinical trial solutions, today announced the release of Virtual Visits, a new telemedicine feature designed to enable ...

The genetic roots of a disease or disorder do not always grow into clear cut, easily diagnosed clinical features. Even if a parent and child have the same genetic marker implicated in an outcome, such ...