Cytochrome P450 enzymes constitute a vast and diverse superfamily of haem‐containing proteins that orchestrate a broad array of oxidative reactions. Their inherent versatility enables them to catalyse ...

The cytochrome P450 (CYP) enzymes are a protein superfamily involved in the synthesis and metabolism of drugs, toxins and normal cellular components. The CYP family of enzymes have been identified in ...

The human nuclear pregnane X receptor (hPXR) activates cytochrome P450-3A expression in response to a wide variety of xenobiotics and plays a critical role in mediating dangerous drug-drug ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

The superfamily of proteins called cytochrome P450 (CYP) enzymes are involved in the synthesis and metabolism of a range of internal and external cellular components. These enzymes have been ...