DNA methylation plays an important role in separating us genetically from our closest relatives.

Drs. Pallabi Mustafi and Ruben Raychaudhuri at Fred Hutch Cancer Center recently received Young Investigator Awards from the ...

Scientists have created a novel method that could make the detection of multiple cancer types much easier. This method, ...

Single-cell epigenetic analysis has revealed how DNA methylation reshapes insulin and glucagon regulation in pancreatic cells ...

Scientists have developed ThermoCas9, a CRISPR enzyme capable of distinguishing cancer cells from healthy ones by reading DNA methylation patterns, potentially reducing off-target edits. In lab tests, ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

The race for early cancer detection is one that physicians have been running for millennia. In one of humanity’s oldest surviving medical texts, the ancient Egyptian physician Imhotep described 46 ...

In a recent study published in the journal Molecular Psychiatry, a team of researchers conducted a large-scale meta-analysis consisting of an epigenome-wide association study to understand whether ...

Researchers have developed ThermoCas9, a CRISPR enzyme that can distinguish cancer cells from healthy ones by reading DNA methylation patterns. In lab tests, it selectively edited breast cancer cell ...