New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment ...

A new microfluidic chip simplifies detecting and quantifying DNA by analyzing electrical impedance signals that vary based on DNA flowing across a biosensor inside the chip. The proof-of-concept ...

Everyday DNA mutations can help us understand immune function and aging—and even mitigate harm caused by some inherited ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan has ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...

Circulating Tumor DNA as a Prognostic Biomarker for Recurrence in Patients With Locoregional Esophagogastric Cancers With a Pathologic Complete Response PD-1 inhibition is effective in patients with ...

The gene editing treatment targets the relatively common 1717-1G>A splicing mutation, which does not respond to many current ...

A new Nature study suggests DNA mutations in immune cells may drive autoimmune diseases by removing immune system brakes, offering clues for targeted treatments.