DNA double-strand breaks (DSBs) represent a critical form of damage in which both strands of the DNA helix are severed. If left unrepaired or misrepaired, DSBs can lead to chromosomal translocations, ...
Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal ...
How do we find out which protein works in a particular DNA repair pathway? We know that if a DNA repair gene is mutated, cells become more sensitive to DNA damaging agents. Researchers in the 1960s ...
13don MSN
Newborn neurons routinely break then repair DNA during brain cortex formation, study reveals
Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to ...
Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...
Scientists from the Institute of Integrated Cellular and Material Sciences at Kyoto University, together with colleagues, ...
Conceptual illustration showing how high transcriptional activity driven by super-enhancers can lead to DNA breaks at oncogenes. When these breaks are repaired inaccurately, they can give rise to ...
New brain cells may briefly damage their own DNA as they squeeze through the crowded developing brain, according to a new ...
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