This study is reported by Dr. Qianwen Sun’s group from Tsinghua University, Dr. Wei Li’s group from Guangzhou Medical University, Dr. Hui Jiang’s group from Peking University Third Hospital, and Wei ...

Initial transcription by RNA polymerase proceeds through a "DNA scrunching" mechanism, in which the enzyme remains stationary on promoter DNA and pulls into itself downstream DNA. Proposed movements ...

This article explores limitations of chemical synthesis in high-throughput settings and the technical advantages enzymatic ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...