aProximate TM PTCs maintain high expression of key transporters involved in drug handling, including megalin and cubilin, making them ideal for studying drug transporters and drug interactions with ...

Vigabatrin is indicated as monotherapy for children with infantile spasms and as adjunct therapy for adults with refractory complex partial seizures. Vigabatrin is a racemic mixture of two enantiomers ...

Credit: Shutterstock Accurate assessment of glomerular filtration rate in patients with cancer is crucial to determine drug eligibility and dosing, while balancing the risks for undertreatment and ...

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart ...

Magnesium is an important cofactor for numerous enzymes. All ATPase reactions require Mg 2+ –ATP, including those involved in RNA and DNA biologic functions. It opposes calcium actions and acts as a ...

The new Nordic renal diet is a plant-focused meal pattern with reduced phosphorus and protein content and more fiber compared with an average Danish diet. The plant-based new Nordic renal diet may ...

Brivaracetam is an orphan drug for the treatment of symptomatic myoclonus. It is a novel high-affinity SV2A ligand that also displays inhibitory activity at neuronal voltage-dependent sodium channels.