The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

Desmosomes and keratin are now found to regulate the distribution and dynamics of the endoplasmic reticulum (ER). This suggests that a range of ER functions may be coordinated by this intercellular ...

The mitochondria-associated endoplasmic reticulum membranes (MAMs), as a highly heterogeneous membrane contact site, play a key role in maintaining biological communication between the endoplasmic ...

Results overturn assumptions about the body's primary structural building block, opening potential new avenues for treating fibrosis and cancer.