A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...

Embryogenesis is one of the most fundamental and remarkable processes in both animals and plants. It's amazing that after fertilization, a single maternal egg cell can develop into an organism with a ...

Every cell type in the human body carries the same approximately 3.2 billion base pairs of DNA, yet a liver cell behaves nothing like a neuron. The epigenome explains this difference: in each cell, ...

A defanged form of CRISPR, which doesn’t slice or nick DNA, but rather alters the epigenome — the layers of chemical coding that sit on top of DNA and control the activity of genes — has aced its ...

In 2020, an estimated 10 million people lost their lives to cancer. This devastating disease is underpinned by changes to our DNA—the instruction manual for all our cells. It has been 20 years since ...

In a recent study posted to the preprint server Research Square* while under review for publication in Epigenetics & Chromatin, researchers develop and characterize a highly specific EpiEditing system ...

Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription ...

Sizable investments. High-profile appearances at industry events. Unique development platforms. These elements would augur well for companies of any kind—and companies hoping to bring epigenome ...

A one-off injection might be able to permanently reduce the risk of heart disease by reversibly switching off a gene in the liver, according to a study in mice. The findings suggest that the approach ...

Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription ...