Long-term follow-up of the CESS 81 and CESS 86 Ewing sarcoma trials. Eliciting early-response signals from first-in-human clinical trials and validation of prognostic scores in aggressive biology bone ...
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show ...
- Company Initiating Planning of Phase 2 Trial of Elraglusib in Children, Adolescents, and Adults with Refractory/Resistant Ewing Sarcoma CHICAGO and FORT WORTH, Texas, July 17, 2025 (GLOBE NEWSWIRE) ...
ADVL1522: A phase 2 study of IMGN901 (lorvotuzumab mertansine; IND# 126953, NSC# 783609) in children with relapsed or refractory Wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, ...
CHICAGO -- High-dose ifosfamide proved more effective at prolonging event-free survival (EFS) and overall survival (OS) than topotecan plus cyclophosphamide in relapsed/refractory Ewing sarcoma, ...
A research team reports finding two subgroups of Ewing sarcoma that respond differently to targeted drug therapy. Ewing sarcoma is a fast-growing form of bone and soft tissue cancer that strikes about ...
Children and adolescents with metastasized Ewing sarcoma have a lower survival rate than those whose cancer cells remain at the primary tumor site. However, a new discovery by researchers with St.
In studies using mice grafted with human Ewing sarcoma tissue, researchers have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, ...
Survival rates from small trial suggest that adding pazopanib to standard treatment for Ewing sarcoma in children may extend lives without adding severe toxicity.
MSK has special expertise in treating childhood cancers like Ewing sarcoma — which usually starts in bone. A surgical technique called distraction osteogenesis allows children to be treated without ...
Ewing sarcoma is one of the most common bone cancers seen in children, and if it spreads, it can be deadly. One study found that under a quarter of children with multi-metastatic Ewing sarcoma ...