Amyloid diseases are a group of progressive disorders including Alzheimer's disease, Parkinson's disease and prion diseases, many of which lack effective cures. These amyloid diseases are commonly ...

Collagen is a building block that can be hierarchically assembled into diverse morphological structures that are dynamically adaptive in response to external cues. Materials scientists have limited ...

Powerful microscopes have allowed researchers to see what exactly holds paper together. Tiny strands of cellulose known as fibril bridges seem to play a crucial role, according to a study published ...

The quantification of collagen fibril size is a major issue for the investigation of pathological disorders associated with structural defects of the extracellular matrix. Second-harmonic generation ...

Adamcik et al. then applied infrared (IR) spectroscopy to further understand the correlation between nanomechanical properties and the chemical secondary structure heterogeneity of single fibrils and ...

Amyloid fibrils are deposits of proteins in the body that join together to form microscopic fibres. Their formation has been linked to many serious human diseases including Alzheimer's, Parkinson's ...

Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer's, these liquid-like droplets can form solid-like clumps known as fibrils. This ...

Researchers have discovered a new type of transition in protein folding: amyloid crystals formed from amyloid fibrils by a decrease in energy. The crystals are even more stable than the fibrils, which ...

Two papers in PNAS add to the growing body of work aimed at understanding the molecular interactions involved in the formation of amyloid fibrils (see related news story). Writing in last week's early ...

Bucking conventional, i.e., left-leaning, wisdom for amyloid fibrils, Aβ fibrils extracted from the brains of three people with Alzheimer’s disease all twisted to the right. This is apparent in the ...

Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer's, these liquid-like droplets can form solid-like clumps known as fibrils. This ...

This is a preview. Log in through your library . Abstract Amyloid-β (Aβ) fibrils exhibit self-propagating, molecular-level polymorphisms that may contribute to variations in clinical and pathological ...