The laminin-411 protein is vital for the formation of the myelin membrane by oligodendrocytes, report researchers from Japan. Furthermore, the A4G47 peptide from the E8 region of laminin-411 was found ...

Scientists from Oregon Health & Science University (OHSU) and the University of Edinburgh have discovered that a little-understood junction that connects neurons to oligodendrocyte precursor cells ...

New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fibers.

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases ...

In the brain, it is not only important that nerve cells send signals, but also how quickly they can do so. In order for information to flow smoothly, a kind of biological insulation is necessary. The ...

Oligodendrocytes are specialised glial cells responsible for the formation and maintenance of myelin sheaths around axons in the central nervous system (CNS). Myelin, a multilamellar membrane rich in ...

Demyelinating diseases, including multiple sclerosis (MS) and Charcot-Marie-Tooth (CMT) disease, present a substantial and escalating burden. Each of these conditions afflicts approximately three ...

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells, according to a novel study. Myelin is an insulating sheath around axons -- the processes ...

A lab study suggests cyclodextrins may help support myelin sheath repair in MS by reducing harmful fat buildup in immune cells.

Despite being one of the most common and well-known neurodegenerative diseases, multiple sclerosis (MS) remains difficult to treat. However, new research from scientists at Cincinnati Children’s ...