CNS toxicity remains one of the leading causes of failure in drug development, yet it is rarely detected in preclinical studies. Among these risks, seizure liability is one of the most challenging and ...
San Diego, California — Smaller lesionectomy resections in the surgical treatment of seizures appear to be just as effective as larger resections in select children, sparing patients the functional ...
CRISPR-based screening in drug discovery provides a robust methodology for unbiased, high-throughput interrogation of gene function. This technology enables researchers to identify and validate ...
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