Polyamines are small, positively charged molecules—primarily putrescine, spermidine and spermine—that accumulate in plant cells in response to environmental stress. They are synthesised from amino ...
A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of pain and opening new paths for targeted therapies. Study: ...
A Phase 1 clinical study showed that DFMO treatment may provide metabolic benefits to preserve β cell function and health in T1D. The research is part of a multi-site clinical trial led by Indiana ...
Japanese researchers investigated how polyamines affect the functional profile of monoclonal antibodies and their production from CHO cells, and found that spermidine supplementation contributes to ...
A Phase 1 clinical study showed that DFMO treatment may provide metabolic benefits to preserve β cell function and health in T1D. From the Phase 1 dose range finding study of CPP-1X in patients with ...
A Phase 1 clinical study showed that DFMO treatment may provide metabolic benefits to preserve β cell function and health in T1D. MINNEAPOLIS, Nov. 02, 2023 (GLOBE NEWSWIRE) -- Panbela Therapeutics, ...