The use of colchicine prophylaxis during the process of up-titrating allopurinol slowly to reach target serum urate levels for patients with gout proved necessary to reduce the risk of flares in a ...

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

Credit: Getty Images. The comparative efficacy of these therapies has been extended to patients with stage 3 chronic kidney disease, a common comorbidity in gout. Allopurinol and febuxostat are ...

Gout is the most common type of inflammatory arthritis. Eating foods like red meat, alcohol, and shellfish make the symptoms ...

Man on bed with pillow embrace foot with painful swollen gout inflammation Researchers compared the time to complete resolution of acute gout flare between early and late allopurinol initiation. Among ...

Delaying initiation of ULT during gout flares had no impact on flare severity, duration or recurrence risk. Patient preference and other individualized factors can determine when to start ULT.

Mr. M and the clinician agree that treatment of his acute gout symptoms with an intra-articular corticosteroid is a sensible approach, eliminating concerns about compliance to an oral regimen or ...

Gout flares are associated with cardiovascular events. Treating gout to target serum urate level prevents flares, but whether such treatment can also prevent cardiovascular events is unknown. An ...

The biotech is starting up with partial rights to a drug that’s approved in multiple Asian countries and its executives see ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...