Last time, we looked at the practice of 'measuring' in analytical chemistry. We explained how chemists determine the amount of a substance and evaluate the reliability of those numerical values ...

In the past few years, high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) has matured to a true alternative to antibody-based immunoassays in routine therapeutic drug ...

Hydroxypropyl methyl cellulose (HPMC) stock solution, 2% (wt/vol; ∼86 K nominal molecular weight; 4,000-cP viscosity; Aldrich); prepare 24 h before use as an aqueous 2% (wt/vol) stock solution by ...

High performance liquid chromatography (HPLC) is a separation technique that uses liquid mobile phase to separate the components of a mixture. The sample is first dissolved in a solvent, then forced ...

Polysaccharide-based chiral stationary phases have been developed that comprise chiral selectors immobilized on their support rather than being physically coated. These materials are completely ...

Liquid chromatography (LC) is a chromatographic technique used to separate and analyze mixtures of chemical components in solution, to determine if a specific component is present or absent and, if ...

As analytical technology continues to advance, both regulatory agencies and pharmaceutical companies are keen to avail themselves of these enhancements. In the case of chromatography, evolution from ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

Over the past few decades, chromatography has seen a significant amount of development and progress. Sophisticated equipment has been invented to improve the efficiency of chromatography-based testing ...