Researchers set out to examine the effects of sodium nitroprusside on the thromboxane-mediated contraction and nitric oxide (NO)-independent relaxation pathways and on reactive oxygen species ...
Pulmonary Circulation, Vol. 4, No. 3 (September 2014), pp. 462-470 (9 pages) AbstractEndothelial nitric oxide synthase (eNOS) plays a major role in maintaining pulmonary vascular homeostasis.
Pulmonary Circulation, Vol. 3, No. 4 (December 2013), pp. 898-907 (10 pages) AbstractPulmonary hypertension (PH) is an incurable disease that often leads to right ventricular hypertrophy and right ...
Perinatal exposure to chronic hypoxia induces sustained hypertension and structural and functional changes in the pulmonary vascular bed. We hypothesized that highland newborn lambs (HLNB, 3600 m) ...
PULMONARY hypertension is a serious and relatively frequent complication of the ostiumsecundum type of defect of the atrial septum. 1–4 It increases the symptoms and disability of cardio-respiratory ...
BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...
HAMPTON, N.J., Jan. 23, 2012 /PRNewswire/ -- Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies for critically ill patients, today announced that the ...
The Vascular Biology and Hypertension Program focuses on molecular and cellular approaches to important problems in cardiovascular medicine. Active in clinical trials include novel therapeutic agents ...
Our clinical research team specializes in a variety of themes related to cardiovascular disease. It is our goal as a division that through clinical research, we can improve the care and treatment of ...
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