"Monogenic" diseases, triggered by mutations in just one gene, may actually be more complex than scientists thought.

A study of 470,000 people reveals that the APOE gene could be behind 90% of Alzheimer's cases in the world today.

Background Monogenic disorders are a major cause of fetal structural anomalies. Most genetic diagnoses involve de novo, biallelic or X linked variants; however, inherited variants in autosomal ...

From carrying a first-aid kit in first grade to launching a transformative preventive cardiology program, a Rutgers Health ...

Familial Alzheimer’s disease is a rare, inherited form of Alzheimer’s that usually develops earlier than other forms of the disease. It’s due to specific genetic variants that tend to run in families.

Although not well-defined, vascular age is intended to measure tissue functional decline and age-associated disease, morbidity, and mortality, more accurately than the chronological age alone. The ...

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations—with inherited health problems worsening many generations after exposure. Those ...

Genes not just shape our looks but also hold our health clues. Today, technology powered by genomics and data analytics is decoding these hidden health patterns, translating family history into ...

Early diagnosis of rare diseases in children can significantly improve treatment outcomes and quality of life. Learn symptoms, challenges, and why early detection is crucial for managing pediatric ...