Meiosis -- the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell -- is a major crossroads in all organisms reproducing sexually. Yet, how the cell ...

In the choreography of meiosis—the process responsible for sex cell division in all eukaryotic life—the pairing of homologous chromosomes (homologs) is essential. Errors in this process can lead to an ...

Where would we be without meiosis and recombination? A new article describes how proteins called SUMO and ubiquitin and molecular machines called proteasomes play a crucial role in DNA recombination ...

A research collaboration based in Kumamoto University (Japan) has clarified how homologous chromosome pairing--a process necessary for sperm and egg formation where paternally- and maternally-derived ...

Mitosis and meiosis are both processes by which cells reproduce, but there are distinct differences between the two. While new cells are generated during mitosis, meiosis is a special type of cell ...

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning ...

Without Holliday junctions, the chromosome zipper fell apart, new DNA breaks re-started forming, and meiosis could no longer proceed correctly. "This study uncovers a simple but elegant feedback loop, ...

Scientists are working to create human eggs in a laboratory dish, but the process is proving to be more challenging than expected.

1. The cytological work on record is briefly surveyed. There are reports on only nineteen species. Work has been confined to members of the tribe Cereeae, which is the most highly evolved tribe in the ...

High-resolution images show excess DNA double-strand breaks formed in DEHP-exposed nuclei destined to become egg cells. Mid-pachytene nuclei (chromosomes in blue) in germlines dissected from control ...