A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...

Living organisms are complex systems with scales of organization spanning the range from Angstroms to meters. Even when consideration is limited to single cells and smaller, there is still a range of ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can ...

To ensure that the tissue structures of biological samples are easily recognisable under the electron microscope, they are treated with a staining agent. The standard staining agent for this is ...

DAPI, or 4,6-diamidino2-phenylindole, is a fluorescent nucleic acid dye used to preferentially stain double-stranded DNA. There is some evidence that it preferentially binds AT clusters present in the ...

Sensing: point-of-care sensors, mobile-phone enabled sensors, field-based sensing and measurement systems with applications in mobile health and telemedicine, environmental monitoring (for example, ...

Cryo-EM is referred to as a form of EM where a transmission electron microscope (TEM) is used to obtain the image of radiation-sensitive specimens under cryogenic conditions. The phrase cryo-EM is ...