Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

To ensure our bodies function correctly, the cells that compose them must operate properly. Imagine a cell as a bustling city where tiny parts called organelles move, reorganize, and respond to ...

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy. The advancements could help provide future insight into ...

Sensing: point-of-care sensors, mobile-phone enabled sensors, field-based sensing and measurement systems with applications in mobile health and telemedicine, environmental monitoring (for example, ...

To ensure that the tissue structures of biological samples are easily recognisable under the electron microscope, they are treated with a staining agent. The standard staining agent for this is ...

Traditional fluorescence microscopy techniques collect only a small amount of the light emitted from a sample at any one time, so a route to improving their efficiency is to capture more of that light ...

A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can ...

DAPI, or 4,6-diamidino2-phenylindole, is a fluorescent nucleic acid dye used to preferentially stain double-stranded DNA. There is some evidence that it preferentially binds AT clusters present in the ...

Cryo-EM is referred to as a form of EM where a transmission electron microscope (TEM) is used to obtain the image of radiation-sensitive specimens under cryogenic conditions. The phrase cryo-EM is ...