Queen's University Belfast-led research reports on a multicenter trial finding no significant reduction in pulmonary exacerbations with hypertonic saline or carbocisteine over 52 weeks among adults ...
Mucoactive agents did little to stave off pulmonary exacerbations of non-cystic fibrosis bronchiectasis, the CLEAR trial showed. In the two-by-two factorial trial testing hypertonic saline and ...
People with cystic fibrosis who have clinical evidence of lung disease are prescribed rhDNase as the first choice of mucoactive agent. Sticky mucus accumulates in the lungs in people with cystic ...
In a recent study published on the bioRxiv* preprint server, researchers evaluate the effects of mucociliary active molecules on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection ...
Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR). CFTR regulates ion transport across the lung epithelia, ...