The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together.

A new study reports that the circadian clock gene BMAL1 and the cell cycle checkpoint regulator WEE1 are significantly ...

Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices. The same is now possible in gene ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

South Korean researchers have developed a universal gene-regulatory platform that allows a single genetic design to be ...

The ability to precisely adjust the expression of genes inside the human body — ramping up protective ones and tamping down harmful ones — holds ...

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...

Prediction of Anthracycline Benefit in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Early-Stage Breast Cancer by the MammaPrint 70-Gene Signature for Patients Enrolled ...

Researchers from Children's Hospital of Philadelphia (CHOP) have tested a preclinical model for an experimental gene therapy designed to treat multiple sulfatase deficiency (MSD), a disorder that ...

Researchers in India have launched AgingHallmarksDB, an interactive platform integrating 3,111 aging-associated genes across ...

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they ...