Get live NFL Week 1 odds, betting lines, spreads and over/unders for this week’s games. Learn how to wager on NFL spreads at the top betting sites.

The SportsLine Projection Model is calling for the Vikings to walk away with a 22-20 victory at home over Green Bay. Minnesota to win is trading at $0.53 per share, while the Packers are trading at $0.47 per share to beat the Vikings. Claim the latest Underdog Predict promo code here and register with the Underdog promo code CBS:

The SportsLine computer simulation has locked in a longshot Week 1 NFL parlay that pays out $1 million for a $10 wager

The Tampa Bay Buccaneers have their season opener in just a few days, and we're making five predictions.

Get expert picks and score predictions for the Patriots vs. Seahawks Week 1 opening game. Breakdown of spread, odds, and game analysis from MassLive.

Here's a look at NFL Week 1 trades you can make for NFL player props on Kalshi and Polymarket prediction markets

NFL power rankings before NFL Week 1 games rank every team by Super Bowl odds, with Chiefs, Rams, Ravens, Bills, Seahawks, Chargers, 49ers at top.