Tylenol and nonsteroidal anti-inflammatory drugs (NSAIDs) are both effective pain and fever reducers. NSAIDs work differently from Tylenol and have the additional benefit of decreasing inflammation.

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...

In the U.S., six non-steroidal anti-inflammatory drugs (NSAIDs) are most commonly used to manage pain and inflammation. While this drug class is widely relied upon, it is also associated with ...

This story was originally published on April 18, 2025, and has been updated. On Monday, President Trump announced that the Food and Drug Administration would be discouraging the use of acetaminophen ...