A comprehensive review finds that AML cells commonly overcome epigenetic drugs through compensatory chromatin and transcriptional adaptation, favoring biomarker-selected combinations and deeper ...
A new review in the Chinese Medical Journal maps how epigenetic modifications and metabolic reprogramming fuel each other in ...
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in ...
Hepatocellular carcinoma (HCC) cells undergo extensive metabolic reprogramming, including alterations in glucose, lipid, and amino acid metabolism, to ...
A new review published in Genes & Diseases explores the intricate epigenetic regulatory network of long noncoding RNAs (lncRNAs) in hepatocellular carcinoma (HCC), shedding light on the profound ...
Housheng Hansen He (left) – Professor in the Department of Medical Biophysics at the University of Toronto and Senior Scientist at Princess Margaret Cancer Centre (both Canada) – investigates the ...
Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...
Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...
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