Striking nucleolar lesions occur in cultured cells after exposure to supranormal temperatures. These lesions appear at 42°C and consist of a loss of the granular ribonucleoprotein (RNP) component and ...
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...
Malfunction of cellular condensates is a disease mechanism relevant for congenital malformations, common diseases, and cancer, new research suggests. Most proteins localize to distinct protein-rich ...