Mycobacterium tuberculosis infects the respiratory tract and establishes a complex interplay with the host immune system. Upon inhalation, bacilli are phagocytosed by alveolar macrophages but evade ...

Mycobacterium tuberculosis harbours two expansive multigene families, designated PE and PPE, whose members collectively constitute around 10 % of the bacillary coding potential. These proteins are ...

lasma metabolomic analysis in active tuberculosis patients and healthy controls. Cerebral tuberculosis (CTB), a severe and often fatal form of central nervous system (CNS) tuberculosis, poses ...

Presented at the annual meeting of the Massachusetts Medical Society, Boston, May 21, 1940. Select the format you want to export the citation of this publication.

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of ...

Tuberculosis (TB) has a long history that dates back thousands of years. Advances in research and understanding of how the infection transmits have led to improvements in treatments and preventive ...

Tuberculosis lives and thrives in the lungs. When the bacteria that cause the disease are coughed into the air, they are thrust into a comparatively hostile environment, with drastic changes to their ...

Tuberculosis is often seen as a threat of the past. But it remains a significant concern worldwide, with international travel spreading the disease. While tuberculous is rare in Australia, and we no ...

The infant tuberculosis vaccine, BCG, prevents severe tuberculosis disease, but protection is rarely durable beyond childhood. New tuberculosis vaccines are being developed for the prevention of ...

Scientists discovered genes in the tuberculosis bacterium that becomes essential for the pathogen's survival when it's exposed to air through coughing. These genes could be targets for new therapies ...