Preclinical studies indicate that cavity-resident macrophages in the peritoneal and pleural spaces contribute to immunosuppression and cancer progression. While these macrophages typically accumulate ...

Pleural diseases affect the pleural tissue that lines the inside of the chest cavity and covers the outside of the lungs. The visceral pleura (which covers the lung) and the parietal pleura (which ...

To investigate their recruitment, Gata6-iCreER mice were crossed with Cd45-Dre and R26-tdT mice, enabling specific lineage tracing of cavity macrophages. Flow cytometry and immunofluorescence ...