Polyethyleneimines (PEIs) are extensively researched as non-viral vectors for gene and medication delivery because of their capacity to condense nucleic acids into nanoparticles known as polyplexes. 1 ...

Scientists from Skoltech (part of the VEB.RF group) and the University of Potsdam have developed a physical theory that sheds light on how molecular motors organize the three-dimensional structure of ...

Scientists developed a charge-free polymer-DNA complex that boosts cellular DNA uptake 14-fold in mice, avoiding the harmful inflammation caused by current methods. Many existing options rely on ...

When a gene is turned on in a cell, it creates a ripple effect along the DNA strand, changing the physical structure of the ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Gene syntax alters DNA supercoiling to amplify or suppress nearby genes. This could improve the effectiveness of gene ...