Intrinsically disordered proteins (IDPs) can dynamically change their conformations depending on their external environment and can, therefore, bind to different compounds. However, they are difficult ...

Determining protein structures requires crystals, but getting proteins to crystallize has long depended on a slow, unpredictable process of trial and error ...

Putting the method to the test To further validate the approach, the team grew more than 1,000 protein crystals and determined the atomic structures of 28 distinct protein-DNA designs. Despite ...

Dr. Lynch is a quantitative and computational scientist focused on applications in structural biology and image analysis. Her work focuses on how we can use imaging methods to better detect and ...

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms. Crystallization enables scientists to determine ...

Our facility supports production and purification of high quantity and purity protein samples. We have instrumentation for the growth, cell harvesting, and lysis of large volume bacterial and insect ...