Here we report the creation of a predominantly β-structured mini-protein motif. The design target is based on the naturally occurring toxin hand (TH) motifs that are composed of four disulfide bonds ...

A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Only recently appreciated as critical components of cellular functions, unstructured stretches of amino acids called SLiMs are key to viral-host interactions. During an early COVID-19 lockdown in ...

It is difficult to underestimate the importance of telomerase, an enzyme that is the hallmark of both aging and the uncontrolled cell division associated with cancer. In an effort to understand and ...

Rajshekhar Gaji was staring at something that should not exist. Under his microscope, parasites that should have been ...

How did life originate? Ancient proteins may hold important clues. Every organism on Earth is made up of proteins. Although all organisms—even single-celled ones—have complex protein structures now, ...

Forbes contributors publish independent expert analyses and insights. Synthetic biology author. This article is more than 4 years old. Motif’s prolamin technology in action via a plant-based cheese ...