Doug Whitney, 76, carries a rare PSEN2 genetic mutation that causes early-onset Alzheimer's but shows no cognitive decline ...

Alzheimer’s disease is characterized by certain key changes in the brain. Among them are the development of two kinds of ...

Tau protein is a microtubule-associated protein, widely present in the central nervous system. It plays a key role in maintaining and regulating the structure and function of neurons. In ...

In addition, the team discovered that plasma total tau—not just the modified pTau217 form—was elevated in newborns. This is ...

Normally, Tau proteins stabilize microtubules and support neuronal function, but in neurodegenerative diseases such as ...

Disabling a clock protein shields the brain from Alzheimer’s effects—hinting at a new path for neuroprotection. Disrupting ...

A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease ...

Newly reported research headed by a team at the Perelman School of Medicine at the University of Pennsylvania points to a potential gene therapy approach to neurodegenerative disorders characterized ...

Please provide your email address to receive an email when new articles are posted on . Phase 1b trial of BII080 demonstrated dose-dependent and sustained reduction of tau protein in CSF, as well as ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...

Espresso compounds inhibit the aggregation of tau proteins- one of the hallmarks of Alzheimer’s disease (AD). The corresponding study was published in the Journal of Agricultural and Food Chemistry.

A gene encoding a protein linked to tau production -- tripartite motif protein 11 (TRIM11) -- was found to suppress deterioration in small animal models of neurodegenerative diseases similar to ...