The factors involved in the removal of RNA primers during plastid DNA (ptDNA) replication have been unclear. We now identify a plastid-localized 5′–3′ exonuclease (PEN1) that mediates the removal of ...
The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets. Thomas Cech. W.W. Norton; 304 pages; $28.99 and £23.99 All this is the subject of Thomas Cech’s new book, “The Catalyst”. The author ...
Innovative approaches to controlled nucleobase-modified RNA synthesis are urgently needed to support RNA biology exploration and to synthesize potential RNA therapeutics. Here we present a strategy ...