Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Contrary to misconceptions among medical professionals and patients alike, individuals born with sickle cell trait (SCT) show no risk of experiencing the acute pain crises known to occur with sickle ...

This article is part of “Innovations In: Sickle Cell Disease,” an editorially independent special report that was produced with financial support from Vertex Pharmaceuticals. Kalpna Gupta was in a ...

A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell ...

Please provide your email address to receive an email when new articles are posted on . Less than one-third of patients who went to the ED with acute sickle cell disease pain received a first opioid ...

Given the remarkable advances seen with gene therapies for sickle cell disease (SCD), it may seem counterintuitive to suggest the space may be in need of more therapies that have already been ...