Mutations in 3 genes (SPG4, SPG3, and SPG31) are implicated in one half of the autosomal dominant hereditary spastic paraplegias, which are part of the larger group of hereditary spastic diplegias ...

Mike Wolanin | The Republic Kyle Alumbaugh demonstrates how he uses his wheelchair ramp participate in 5k run, walk or roll to raise awareness for Hereditary Spastic Paraplegia and Primary Lateral ...

Hereditary spastic paraplegia (HSP) is the name given to a group of inherited neurological disorders characterized by progressive stiffness or tightness of the muscles (spasticity) in the lower limbs.

Hereditary spastic paraplegias refers to a clinically and genetically heterogenous disorders that are characterised by lower extremity spasticity and weakness. When the symptoms of this disease behind ...

Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic ...

Hereditary spastic paraplegias (HSP) are a group of hereditary diseases that result in progressive loss of motor function in the lower limbs, and mutations in many different genes have been implicated ...

"Hereditary Spastic Paraplegias Market Insights, Epidemiology, and Market Forecast-2032"The hereditary spastic paraplegias treatment market is poised for significant expansion over the coming years, ...

The Qiang Laboratory concentrates on using human induced pluripotent stem cell (hiPSC) based technologies to establish in vitro (distinct phenotypical CNS neuronal cultures) and ex vivo (3d forebrain ...

TUCSON, Ariz. (KGUN) — Sitting in his wheelchair, junior at Catalina Foothills High School Ethan Bennett was pushed onstage by his partner Lily Rhodes. While he can move around, he can't walk or talk.

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Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...