Both hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain, respectively. Diagnosis ...

Investigators found patients with acute coronary syndrome were 3 times more likely to die in the hospital. Patients with thrombotic thrombocytopenic purpura (TTP) face a higher risk of morbidity and ...

Molecular details of ADAMTS13 binding by autoantibodies reveal, for the first time, the mechanism of inhibition of ADAMTS13 by those autoantibodies and suggest an avenue for therapeutic intervention.

An organism provisionally classified as a microtatobiote, order of rickettsiales, family of bartonellaceae, was isolated from two patients with hemolytic-uremic syndrome (HUS) and from another with ...

Congenital thrombotic thrombocytopenic purpura (TTP) results from severe hereditary deficiency of ADAMTS13. The efficacy and safety of recombinant ADAMTS13 and standard therapy (plasma-derived ...

Plasma exchange is the essential treatment for TTP, but it has no known benefit for patients with cancer-induced or drug-induced TMA. We will describe cancer-induced and drug-induced TMA using the ...

Acquired thrombotic thrombocytopenic purpura (acquired TTP, or aTTP) is a rare blood disorder that results in blood clots in small blood vessels around your body. These clots can slow the flow of ...

The COVID-19 pandemic has prompted the rapid development and administration of various vaccines worldwide, with some reports linking these vaccines to immune thrombotic thrombocytopenic purpura (TTP).

The hallmark of both post-CABG HITT and post-CABG TTP is unexplained thrombocytopenia and an evidence of thrombotic complications. HITT is usually present with either venous or arterial thrombosis, or ...