College football fans have a packed weekend with a season-high five Top 25 matchups on Saturday. The action kicks off with No. 10 LSU visiting No. 17 Vanderbilt followed by No. 5 Mississippi at No. 9 Georgia.

Vanderbilt is coming off an open week; LSU (5-1, 2-1) defeated South Carolina 20-10 in Baton Rouge, Louisiana on Oct. 11. The week off for Vanderbilt football came after it suffered its first loss of the 2025 season when Alabama avenged a 2024 loss with a 30-14 victory.

IU football travels to Eugene, Oregon on Saturday, October 11 for a top-10 matchup against the Oregon Ducks. The Hoosiers and Ducks will kick off at 3:30 p.m. ET on CBS at Autzen Stadium. Both teams are 5-0 and are off this weekend.

The top-ranked Ohio State Buckeyes, led by quarterback Julian Sayin, face the No. 17 Illinois Fighting Illini, led by quarterback Luke Altmyer, on Saturday, Oct. 11, 2025 at Memorial Stadium in Champaign,

The broadcast network and kickoff time will be determined following the conclusion of games on Saturday, Oct. 18.

The final injury report for Saturday's game between Kansas State and TCU was released 90 minutes before kickoff. Here's who is out.

The No. 21 Arizona State Sun Devils face the Utah Utes, led by quarterback Devon Dampier, on Saturday, Oct. 11, 2025 at Rice-Eccles Stadium in Salt Lake City, Utah.

There are three ranked-on-ranked pairings in the SEC alone, headlined by the top-10 clash matching No. 5 Mississippi and No. 7 Georgia between the hedges. Elsewhere in ‘just means more land,’ No. 6 Alabama hosts No.