Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

The establishment and maintenance of neuronal identity are critically dependent on a finely tuned interplay between transcription factors and the epigenetic landscape. Central to this network is the ...

New research reveals that a fundamental process in bacterial gene regulation called sigma cycle, long thought to involve the release of a key protein, sigma factor, might not be universal, opening new ...

In a paper published on aBIOTECH, so far, the authors have for the first time comprehensively analyzed the ...

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is turned on, the production of proteins or other substances is promoted; when ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can ...