Transforming Growth Factor Beta (TGF‐β) signalling pathways are integral to a wide array of cellular processes, ranging from embryonic development to tissue homeostasis and immune regulation. TGF‐β ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

Novel TROP2-targeted CAR T cells with high specificity and sustained efficacy for solid tumors in animal models. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Understand inflammation, remodelling and the three techniques that target scars in the epidermis, dermis and below.

Osteoporosis is a degenerative disease characterized by decreased bone mass and damage to bone microarchitecture, as well as increased bone fragility. Previous research showed that the conserved ...

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health ...

LA Times Studios may earn commission from purchases made through our links. If you continually chase every so-called “miracle” ingredient (retinol, vitamin C, hyaluronic acid), you’re not alone.