A growing body of research has identified a hidden immune defect, not written in DNA, that helps explain why certain people ...

TLR4 recognizes bacterial-derived lipopolysaccharides and activates IRF3 via the adapter protein TRIF, contributing to the induction of type I IFN genes. Within endosomes, TLR3, TLR7, and TLR9 ...

SIGLEC‑1 expression correlates with disease activity in patients with lupus erythematosus during type I interferon blockade ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...

New whole-blood assay for detecting immune autoantibodies promises to revolutionize diagnostics, offering rapid, cost-effective solutions to detect inborn errors of immunity and neutralizing ...

Advances in the treatment of gastroenteropancreatic poorly differentiated neuroendocrine carcinoma at our hospital. This is an ASCO Meeting Abstract from the 2024 ASCO Gastrointestinal Cancers ...

Please provide your email address to receive an email when new articles are posted on . “These findings suggest that IFN-I blocking agents may be particularly effective in treating skin manifestations ...

SARS-CoV-2 triggers the production of the antiviral protein IFN- γ , which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN- y production ...