All Windows PCs come with a built-in security feature called Windows Defender Application Control (WDAC), which helps prevent unauthorized software from running by allowing only trusted applications.
Microsoft plans to remove Defender Application Guard from Office by December 2027, starting with the February 2026 release of Office version 2602. The Microsoft Defender Application Guard for Office ...
The Windows firewall is a fine place to start, but there are better options.
Microsoft has released the July 2024 preview update for Windows 10, version 22H2, with fixes for Windows Defender Application Control (WDAC) issues causing app crashes and system memory exhaustion.
For most people using a supported and fully updated Windows 11 computer, yes: Microsoft Defender Antivirus and the other protections inside Windows Security are sufficient as the primary antivirus.