A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A new single-molecule flow-stretch assay enables real-time observation of DNA-protein interactions to identify the molecular ...

Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in ...

Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease. Now, a multi-institutional team led by The ...

A project at Switzerland's EPFL research center has developed a new variant of fluorescence lifetime imaging microscopy (FLIM) that could substantially accelerate the imaging operation. Described in ...

For Amy Engevik, an epithelial cell biologist at the Medical University of South Carolina who studies cell function in the gastrointestinal tract, protein location matters more than abundance. She ...

Polycyclic aromatic hydrocarbons (PAHs) have been detected in interstellar clouds. Credit: JWST/NASA The James Webb Space Telescope (JWST) has unlocked the depths of interstellar space with ...

The polarized diSPIM microscope, which can image full 3D orientation and position of molecules in cells. The instrument was constructed in the Hari Shroff lab at the National Institute of Biomedical ...