Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show ...

Long-term follow-up of the CESS 81 and CESS 86 Ewing sarcoma trials. Eliciting early-response signals from first-in-human clinical trials and validation of prognostic scores in aggressive biology bone ...

ADVL1522: A phase 2 study of IMGN901 (lorvotuzumab mertansine; IND# 126953, NSC# 783609) in children with relapsed or refractory Wilms tumor, rhabdomyosarcoma, neuroblastoma, pleuropulmonary blastoma, ...

Children and adolescents with metastasized Ewing sarcoma have a lower survival rate than those whose cancer cells remain at the primary tumor site. However, a new discovery by researchers with St.

Ewing sarcoma is the second most frequent bone tumour in children, adolescents, and young adults. There is no specific treatment for this disease and current management is still limited to surgery, ...

CHICAGO -- High-dose ifosfamide proved more effective at prolonging event-free survival (EFS) and overall survival (OS) than topotecan plus cyclophosphamide in relapsed/refractory Ewing sarcoma, ...

A research team reports finding two subgroups of Ewing sarcoma that respond differently to targeted drug therapy. Ewing sarcoma is a fast-growing form of bone and soft tissue cancer that strikes about ...

In studies using mice grafted with human Ewing sarcoma tissue, researchers have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, ...

MSK has special expertise in treating childhood cancers like Ewing sarcoma — which usually starts in bone. A surgical technique called distraction osteogenesis allows children to be treated without ...

Survival rates from small trial suggest that adding pazopanib to standard treatment for Ewing sarcoma in children may extend lives without adding severe toxicity.